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Transcriptomic taxonomy and neurogenic trajectories of adult human,macaque, and pig hippocampal and entorhinal cells
Affiliation:1. Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA;2. Department of Genetics, Yale School of Medicine, New Haven, CT 06510, USA;3. Neurogenomics Group, Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Medical Research Institute (IMIM), DCEXS, Universitat Pompeu Fabra, 08003 Barcelona, Catalonia, Spain;4. Department of Biomedical Engineering, Yale Stem Cell Center and Yale Cancer Center, and Human and Translational Immunology Program, Yale University, New Haven, CT 06520, USA;5. Program in Cellular Neuroscience, Neurodegeneration and Repair, Departments of Neurology and of Neuroscience, Yale School of Medicine, New Haven, CT 06536, USA;6. Department of Pathology, Brady Memorial Laboratory, Yale School of Medicine, New Haven, CT 06510, USA;7. Waisman Center and Department of Neuroscience, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, USA;8. Kavli Institute for Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA;9. Departments of Psychiatry and Comparative Medicine, Program in Cellular Neuroscience, Neurodegeneration and Repair, and Yale Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA
Abstract:
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  • Keywords:single-cell RNA-seq  hippocampus  entorhinal cortex  adult neurogenesis  neuroblast  immature neurons  doublecortin  evolution  METTL7B  Alzheimer’s disease
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