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Uncompetitive,adduct-forming SARM1 inhibitors are neuroprotective in preclinical models of nerve injury and disease |
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| Affiliation: | 1. Biology Department, Nura Bio Inc., South San Francisco, CA 94080, USA;2. Chemistry Department, Nura Bio Inc., South San Francisco, CA 94080, USA;3. WuXi AppTec, Research Services Division, 6 Cedarbrook Drive, Cranbury, NJ 08512, USA;4. Gfree Bio, 10601 FM 2222 Ste R PMB 206, Austin, TX 78730, USA |
| Abstract: |  |
| Keywords: | NAD hydrolase SARM1 uncompetitive inhibition small-molecule inhibitor axon degeneration neurodegenerative disease neuroprotection neurofilament light |
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