A case of heterotopic pancreas mimicking an intestinal neuroendocrine tumor in 18F-DOPA PET-CT and a review of the literature |
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Institution: | 4. Canon Medical Systems Corporation, Otawara, Tochigi, Japan |
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Abstract: | 18-Fluoro-L-dihydroxyphenylalanine positron emission tomography/computed tomography (18F-DOPA PET-CT) is a nuclear medicine imaging modality indicated for the diagnosis and staging of neuroendocrine tumors (NETs), particularly for the midgut tumors, due to its excellent sensitivity and specificity. Its performance for the detection of foregut-derived NETs (duodenopancreas and proximal jejunum) and for the detection of hindgut-derived NETs is poor and inferior to PET somatostatin receptor imaging such as DOTATOC PET-CT and even inferior to somatostatin analog scintigraphy (octreoscan). There are few studies in the literature on heterotopic pancreas (HP) which is a rare entity, and which can be in some cases a false positive in 18F-DOPA PET-CT. We report a case of HP showing focal uptake on 18F-DOPA PET-CT mimicking an intestinal NET. This case suggests that HP should be included as a possible false positive on 18F-DOPA PET-CT. |
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Keywords: | Heterotopic pancreas PET-CT 18F-DOPA NET DOTATOC TEP-TDM 18F-DOPA DOTATOC Pancréas ectopique Tumeur neuro-endocrine Médecine nucléaire Onco-digestive Case-report Revue de la littérature radiologie |
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