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Myeloid cell interferon secretion restricts Zika flavivirus infection of developing and malignant human neural progenitor cells
Affiliation:1. Wellcome MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge CB2 0AW, UK;2. Division of Academic Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0QQ, UK;3. Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge CB2 0RE, UK;4. Wellcome Sanger Institute, Hinxton CB10 1SA, UK;5. Department of Paediatrics, University of Cambridge, Cambridge CB2 0QQ, UK;6. Department of Virology, University of Cambridge, Cambridge CB2 0QQ, UK;7. Department of Virology, Royal London Hospital, Barts Health NHS Trust, London E1 2ES, UK;8. Manchester Centre for Clinical Neurosciences, Manchester M6 8HD, UK;9. Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham B15 2SY, UK;10. Experimental Medicine and Immunotherapeutics, University of Cambridge, Cambridge CB2 0QQ, UK;11. Centre for Regenerative Medicine and Cancer Research UK Edinburgh Centre, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh EH16 4UU, UK;12. The Pirbright Institute, Guildford, Surrey GU24 0NF, UK;13. Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK
Abstract:
Keywords:glioblastoma  GBM  neural  Zika  flavivirus  oncolytic  microglia  macrophage  myeloid  interferon
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