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Presynaptic FMRP and local protein synthesis support structural and functional plasticity of glutamatergic axon terminals
Affiliation:1. Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York, NY 10461, USA;2. Department of Cell Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York, NY 10461, USA;3. Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York, NY 10461, USA
Abstract:
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  • Keywords:structural plasticity  LTP  protein synthesis  fragile X syndrome  enriched environment  hippocampus  RNA-binding protein
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