Binding and production of insulin-like growth factor-I in rat mammary gland. |
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| Authors: | S Lavandero J F Santibá?ez M P Ocaranza A Ferreira M Sapag-Hagar |
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| Affiliation: | Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago. |
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| Abstract: | 1. Mammary tissue from pregnant rat presents low and high affinity IGF-I functional receptors. 2. Mammary explants from pregnant and lactating rats secrete IGF-I and its production was related to the developmental stage of the gland. 3. An inverse relationship between IGF-I production and tissue binding capacity was observed. |
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