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Optical properties of mice's stool in 550 to 1000 nm wavelength range |
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| Authors: | Helene Isler Catherine Germanier Linda Ahnen Jingjing Jiang Scott Lindner Aldo Di Costanzo Mata Tanja Karen Salvador Sánchez Majos Martin Wolf Alexander Kalyanov |
| Affiliation: | 1. Biomedical Optics Research Laboratory (BORL), Department of Neonatology, University of Zurich and University Hospital Zurich, Zurich, Switzerland;2. Animal Imaging Center (AIC), Institute of Biomedical Engineering, ETH Zurich, Zurich, Switzerland;3. Advanced Quantum Architecture (AQUA) Laboratory, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland |
| Abstract: | The aim of this work was to measure optical properties of stool of mice to provide this relevant wavelength‐dependent behavior for optical imaging modalities such as fluorescent molecular tomography and near‐infrared optical tomography. BALB/c nude female mice were studied and optical properties of the stool were determined by employing the inverse adding‐doubling approach. The animals were kept on chlorophyll‐free diet. Nine stool samples were measured. The wavelength‐dependent behavior of absorption and scattering in 550 to 1000 nm range is presented. The reduced scattering spectrum is fitted to the Mie scattering approximation in the near‐infrared (NIR) wavelength range and to the Mie + Rayleigh approximation in visible/NIR range with the fitting coefficients presented. The study revealed that the absorption spectrum of stool can lead to crosstalk with the spectrum of hemoglobin in the NIR range.  |
| Keywords: | absorption spectra IAD NIROT optical properties of tissue reduced scattering spectra stool of the mouse |