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Back Cover: Protein secondary structure analysis of dried blood serum using infrared spectroscopy to identify markers for colitis screening (J. Biophotonics 3/2018) |
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| Authors: | Jitto Titus Hemendra Ghimire Emilie Viennois Didier Merlin A G Unil Perera |
| Institution: | 1. Department of Physics and Astronomy, Georgia State University, Atlanta, Georgia;2. Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia;3. Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, Georgia;4. Atlanta Veterans Affairs Medical Center, Decatur, Georgia |
| Abstract: | Protein secondary structural alteration in the serum sample as induced by colitis has been demonstrated via the spectral fitting. Using DSS mouse models of acute colitis and IL10‐/‐ for chronic colitis, a significant difference in the integral ratio of Gaussian energy bands representing α‐helix and β‐pleated sheet structures were obtained. Further details can be found in the article by Jitto Titus et al. ( e201700057 ).  |
| Keywords: | anti‐TNFα ATR‐FTIR colitis secondary structure sera |