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Back Cover: Autofluorescence and white light imaging‐guided endoscopic Raman and diffuse reflectance spectroscopy for in vivo nasopharyngeal cancer detection (J. Biophotonics 4/2018)
Authors:Jianji Pan  Zhihong Xu  Rong Chen  Shangyuan Feng  Guannan Chen  Yongzeng Li  Michael Short  Jianhua Zhao  Yasser Fawzy  Haishan Zeng
Affiliation:1. Department of Radiation Oncology, Fujian Provincial Cancer Hospital, Fujian Medical University Cancer Hospital, Fujian Provincial Key Laboratory of Translational Cancer Medicine, Fuzhou, Fujian, China;2. Key Laboratory of Optoelectronic Science and Technology for Medicine, Ministry of Education, Fujian Provincial Key Laboratory for Photonics Technology, Fujian Normal University, Fuzhou, Fujian, China;3. Imaging Unit—Integrative Oncology Department, BC Cancer Agency Research Centre, Vancouver, British Columbia, Canada
Abstract:An integrated 4‐modality endoscopy system combining white light imaging, autofluorescence imaging, diffuse reflectance spectroscopy and Raman spectroscopy technologies was developed for in vivo endoscopic nasopharyngeal cancer detection. Both high diagnostic sensitivity (98.6%) and high specificity (95.1%) for differentiating cancer from normal tissue sites were achieved using this system combined with multivariate diagnostic algorithm, demonstrating great potential for improving real‐time, in vivo diagnosis of cancer at endoscopy. Further details can be found in the article by Duo Lin et al. ( e201700251 )

Keywords:autofluorescence imaging  diffuse reflectance spectroscopy  nasopharyngeal cancer detection  Raman spectroscopy
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