Nonviral delivery systems for small interfering RNAs |
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Authors: | K V Glebova A V Marakhonov A V Baranova M Yu Skoblov |
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Institution: | 1.Research Center for Medical Genetics,Russian Academy of Medical Sciences,Moscow,Russia;2.School of Systems Biology,George Mason University,Fairfax,USA |
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Abstract: | RNA interference is now considered to be the most powerful and promising tool for gene-targeted therapy. Several problems are still to be solved for its successful use in medicine. One of the main issues is efficient siRNA delivery. The review considers various types of nonviral siRNA delivery systems. |
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