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Modelling 'evo-devo' with RNA
Authors:Fontana Walter
Institution:Santa Fe Institute, 1399 Hyde Park Road, Santa Fe, NM 87501, USA. walter@santafe.edu
Abstract:The folding of RNA sequences into secondary structures is a simple yet biophysically grounded model of a genotype-phenotype map. Its computational and mathematical analysis has uncovered a surprisingly rich statistical structure characterized by shape space covering, neutral networks and plastogenetic congruence. I review these concepts and discuss their evolutionary implications.
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