Modelling 'evo-devo' with RNA |
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Authors: | Fontana Walter |
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Institution: | Santa Fe Institute, 1399 Hyde Park Road, Santa Fe, NM 87501, USA. walter@santafe.edu |
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Abstract: | The folding of RNA sequences into secondary structures is a simple yet biophysically grounded model of a genotype-phenotype map. Its computational and mathematical analysis has uncovered a surprisingly rich statistical structure characterized by shape space covering, neutral networks and plastogenetic congruence. I review these concepts and discuss their evolutionary implications. |
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