Characterisation of neurotensin-immunoreactivity in porcine ileum using region-specific radioimmunoassays and chromatographic fractionation: isolation and primary structure of porcine neurotensin |
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| Authors: | C Shaw L Thim C F Johnston K D Buchanan |
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| Institution: | Department of Medicine, Queen's University of Belfast, Northern Ireland. |
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| Abstract: | 1. Neurotensin-immunoreactivity has been characterised in porcine ileum using region-specific radioimmunoassay coupled to chromatographic fractionation. 2. Two immunoreactive peptides were identified. 3. Peptide 1 was immunochemically, chromatographically and structurally identical to bovine neurotensin. 4. Peptide 2 exhibited novel immunochemical and chromatographic characteristics and represents a new neurotensin-related peptide. |
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