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The Proteolytic Profile of Human Cancer Procoagulant Suggests That It Promotes Cancer Metastasis at the Level of Activation Rather Than Degradation
Authors:Nalise Low Ah Kee  Jason Krause  Gregory L. Blatch  Koji Muramoto  Kazuo Sakka  Makiko Sakka  Ryno J. Naudé  Leona Wagner  Raik Wolf  Jens-Ulrich Rahfeld  Hans-Ulrich Demuth  Wojciech P. Mielicki  Carminita L. Frost
Affiliation:1. Department of Biochemistry and Microbiology, Nelson Mandela Metropolitan University, P.O. Box 77000, Port Elizabeth, 6031, South Africa
2. Biomedical Biotechnology Research Unit, Department of Biochemistry, Microbiology and Biotechnology, Rhodes University, P.O. Box 94, Grahamstown, 6140, South Africa
7. Centre for Chronic Disease, College of Health and Biomedicine, Victoria University, Melbourne, VIC, Australia
5. Laboratory of Biomolecular Function, Graduate School of Life Sciences, Tohoku University, Sendai, 981-8555, Japan
6. Department and Graduate School of Sustainable Resource Sciences, Mie University, 1577 Kurima-Machiyacho, Tsu, 514-8507, Japan
4. Probiodrug AG, Weinbergweg 22, 06120, Halle, Germany
8. Department of Drug Design and Target Validation, Fraunhofer-Institute for cell therapy and immunology, Weinbergweg 22, 06120, Halle, Germany
3. Department of Pharmaceutical Biochemistry, Medical University of ?ód?, ul. Muszynskiego 1, 90151, Lodz, Poland
Abstract:
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