GenePro: a Cytoscape plug-in for advanced visualization and analysis of interaction networks |
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Authors: | Vlasblom James Wu Samuel Pu Shuye Superina Mark Liu Gina Orsi Chris Wodak Shoshana J |
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Affiliation: | Structural Biology and Biochemistry Program, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada. |
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Abstract: | MOTIVATION: Analyzing the networks of interactions between genes and proteins has become a central theme in systems biology. Versatile software tools for interactively displaying and analyzing these networks are therefore very much in demand. The public-domain open software environment Cytoscape has been developed with the goal of facilitating the design and development of such software tools by the scientific community. RESULTS: We present GenePro, a plugin to Cytoscape featuring a set of versatile tools that greatly facilitates the visualization and analysis of protein networks derived from high-throughput interactions data and the validation of various methods for parsing these networks into meaningful functional modules. AVAILABILITY: The GenePro plugin is available at the website http://genepro.ccb.sickkids.ca. |
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