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Old drugs, new tricks: using genetically sensitized yeast to reveal drug targets
Authors:Hughes Tim  Andrews Brenda  Boone Charles
Affiliation:Department of Medical Genetics and Microbiology, University of Toronto, Toronto, Ontario, Canada M5G 1L6.
Abstract:A study in this issue of Cell illustrates the power of applying genomic approaches with model systems to characterize the biological activity of small molecules and to identify their cellular targets, which can clarify the mode of action of human therapeutics.
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