PKSIIIexplorer: TSVM approach for predicting Type III polyketide synthase proteins |
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Authors: | Vijayan Mallika Chandrika Sivakumar Krishnankutty Vasudevan Soniya Eppurathu |
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Institution: | 1Plant Molecular Biology, Rajiv Gandhi Centre for Biotechnology, Thycaud P O, Poojappura, Thiruvananthapuram - 695 014, Kerala, India;2Bioinformatics Facility, Rajiv Gandhi Centre for Biotechnology, Thycaud P O, Poojappura, Thiruvananthapuram - 695 014, Kerala, India |
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Abstract: | PKSIIIexplorer, a web server based on 'transductive Support Vector Machine' allows fast and reliable prediction of Type III polyketide synthase proteins. It provides a simple unique platform to identify the probability of a particular sequence, being a type III polyketide synthases or not with moderately high accuracy. We hope that our method could serve as a useful program for the type III polyketide researchers. The tool is available at "http://type3pks.in/tsvm/pks3". ABBREVIATIONS: PKS - Polyketide synthase, CHS - Chalcone synthase, SVM - Support vector machine, MCC - Matthews Correlation Coefficient. |
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Keywords: | Type III polyketide synthase PKSIIIexplorer TSVM Chalcone synthase |
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