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The Effect of Carnitine on Palmitate Oxidation by Pea Cotyledon Mitochondria |
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| Authors: | McNEIL PHILIP HENRY; THOMAS DAVID RICHARD |
| Abstract: | The conditions for maximum O2 uptake by pea cotyledon mitochondriaoxidizing palmitate were established. It was found that CoASH,Mg2+, ATP, malate, and carnitine were necessary additions tothe incubation medium. It is suggested that carnitine combineswith palmitoylCoA to produce palmitoylcarnitine with the releaseof CoASH. The palmitoylcarnitine thus formed may penetrate themembranes of the mitochondria with greater ease than palmitoylCoA. |
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