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Overexpression of HOX genes is prevalent in Ewing sarcoma and is associated with altered epigenetic regulation of developmental transcription programs
Authors:Laurie K Svoboda  Ashley Harris  Natashay J Bailey  Raphaela Schwentner  Eleni Tomazou  Cornelia von Levetzow  Brian Magnuson  Mats Ljungman  Heinrich Kovar  Elizabeth R Lawlor
Affiliation:1.Translational Oncology Program and the Departments of Pediatric and Communicable Diseases; University of Michigan; Ann Arbor, MI USA;2.Pediatrics and Communicable Diseases; University of Michigan; Ann Arbor, MI USA;3.Radiation Oncology; University of Michigan; Ann Arbor, MI USA;4.Pathology, University of Michigan; Ann Arbor, MI USA;5.Children''s Cancer Research Institute; St. Anna Kinderkrebsforschung; Vienna, Austria;6.Department of Pediatrics; Medical University of Vienna; Vienna, Austria
Abstract:
Keywords:epigenetic   Ewing sarcoma   HOX   polycomb
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