| 激光视网膜损伤治疗的实验研究 |
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| 引用本文： | 单清,任华,张杰,焦振宇,钱焕文. 激光视网膜损伤治疗的实验研究[J]. 激光生物学报, 2001, 10(2): 124-127 |
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| 作者姓名： | 单清 任华 张杰 焦振宇 钱焕文 |
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| 作者单位： | 军事医学科学院放射医学研究所, |
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| 基金项目： | 全军“九五”医学科研规划指令性课题! ( 96L0 2 9) |
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| 摘 要： | 为研究碱性成纤维细胞生长因子（basic fibroblast growth factor,bFGF），地塞松和维生素C对激光视网膜损伤的治疗作用，将采用氩离子激光照射致视网膜损伤的青紫蓝灰兔分9组（照射对照组、球后注射bFGF0.5、1.0、2.0μ.k.3D组和地塞米松1.0m.k.3D；肌肉注射bFGF1.0、2.0、4.0μ.k.D组和地塞米松2.0mg加维生素C200.0mg组）。恒河猴分4组（照射对照组、bFGF1.0、2.0μ.k.3D组和地塞米松1.0m.k.3D组）。通过视网膜电流图、检眼镜、眼底照相机、损伤斑面积测量、光镜和电镜观察，结果表明bFGF对视网膜损伤斑有明显的促进修复愈合作用。
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| 关 键 词： | 激光 视网膜损伤 治疗 |
| 文章编号： | 1007-7146(2001)02-0124-04 |
| 修稿时间： | 2001-01-05 |
Study on Treatment of Retina Injured by Laser |
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| SHAN Qing,et al. Study on Treatment of Retina Injured by Laser[J]. ACTA Laser Biology Sinica, 2001, 10(2): 124-127 |
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| Authors: | SHAN Qing et al |
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| Abstract: | To study what effect bFGF,dexamethasone and vitamin C has on laser-induced retina injuries.Chinchilla rabbits and rhesus monkeys whos e retinas were injured by arg on ion laser were divided into nine (exposure contr o l,retrobulbar injection bFGF0.5,1.0,2.0μ.k.3D and dexamethasone 1.0m.k.3D;intra muscular injection bFGF1.0,2.0,4.0μ.k.D,and dexamethasone 2.0 mg addvitamin C 200.0 mg) and four goups(exposure control,retrobulbar injection bFGF 1.0,2.0μ. k.3D and dexamethasone 1.0m.k.3D),respectively.Six items including electroretino gram,ophthalmoscopy,fundua photography,morphometry,histology and ultrastructure were used to examine the therapeutic effect.The results indicated that bFGF coul d accelerate the repair of the retina tissue and prevent the photoreceptor loss in laser injury retina of animals. |
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| Keywords: | laser retina injury therapy |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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