Use of DNA fingerprinting for human population genetic studies |
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| Authors: | Vadim V. Kalnin Olga V. Kalnina Michael I. Prosniak Irina M. Khidiatova Elsa K. Khusnutdinova Khalim S. Raphicov Svetlana A. Limborska |
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| Affiliation: | (1) Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilov St., 117984 Moscow, Russia;(2) Institute of Molecular Genetics, Russian Academy of Sciences, Kurchatov square, 123182 Moscow, Russia;(3) Department of Biochemistry and Cytochemistry, Bashkir Science Center of Ural Branch of Russian Academy of Sciences, 450054 Ufa, Russia |
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| Abstract: | DNA fingerprinting techniques have been used in population genetic studies on many different kinds of organisms. Here, we present new applications for multilocus DNA fingerprint probes in population studies and demonstrate the applicability of DNA fingerprinting to human population genetics, using M13 phage DNA as a probe. The new approach, which is based on a factor method of numerical coding of non-quantitative data (factor correspondence analysis-FCA), shows good agreement between population position, as indicated by the three principal factors, and ethnogenetic proximity. |
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| Keywords: | DNA fingerprinting M13 DNA probe Human population genetics Factor correspondence analysis Ethnogenetic proximity |
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