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Interleukin 1 alpha mRNA in virus-transformed T and B cells |
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| Authors: | T Noma T Nakamura M Maeda M Okada Y Taniguchi Y Tagaya Y Yaoita J Yodoi T Honjo |
| Abstract: | IL-1 alpha cDNA clone was isolated from a T cell line infected by the human T lymphotropic retrovirus type-I (HTLV-I/ATLV). We found significant amounts of mRNA hybridizing to IL-1 alpha cDNA not only in HTLV-I-transformed T cells but also in Epstein-Barr Virus-transformed B cells. A part of IL-2 receptor inducing activity in Adult T cell leukemia (ATL) cell line seems to be due to IL-1 alpha. |
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