Characterization of SE-3, a virulent bacteriophage of Saccharopolyspora erythraea |
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| Authors: | M Smorawinska F Denis C V Déry P Magny R Brzezinski |
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| Affiliation: | Département de Microbiologie, Faculté de Médecine, Université de Sherbrooke, Québec, Canada. |
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| Abstract: | SE-3 is a virulent bacteriophage isolated from a large-scale culture of Saccharopolyspora erythraea, an erythromycin producer. The host range of the phage is narrow, limited to some strains of this species. Another strain of Sac. erythraea, and a strain of Sac. hirsuta, are able to adsorb phage particles but do not sustain their complete multiplication. SE-3 is closely related to the phage SE-5 as shown by DNA restriction mapping. The differences between SE-3 and SE-5 genomes are apparently limited to two DNA segments flanked by short inverted repeats, visualized by electron microscopy. |
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