Regional distribution of choline acetyltransferase and acetylcholinesterase in rabbit brain |
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| Authors: | B. Hetnarski H. M. Wisniewski K. Iqbal J. D. Dziedzic A. Lajtha |
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| Affiliation: | (1) Institute for Basic Research in Mental Retardation, 10314 Staten Island, New York;(2) Center for Neurochemistry, 10035 Ward's Island, New York |
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| Abstract: | Regional distribution of choline acetyltransferase (CAT) and acetylcholinesterase (AChE) in seventeen regions of the rabbit CNS has been determined by means of the cation exchange radiometric method. A significant correlation has been found between the activities of AChE and CAT which allows computation of their potencies. A comparison between activities of the cholinergic enzymes in the human and rabbit brain has been discussed. |
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