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蛋白质糖基化修饰的研究方法及其应用
引用本文:张倩,杨振,张艳贞,王爱丽,安学丽,晏月明. 蛋白质糖基化修饰的研究方法及其应用[J]. 生物技术通报, 2006, 0(1): 46-49
作者姓名:张倩  杨振  张艳贞  王爱丽  安学丽  晏月明
作者单位:首都师范大学生命科学学院,北京,100037
基金项目:国家自然科学基金资助项目(30571154)
摘    要:蛋白质糖基化是一种重要的翻译后修饰,它参与和调控生物体的许多生命活动。随着蛋白质组技术的不断发展,蛋白质糖基化研究越来越受到广泛的重视。本文介绍了蛋白质糖基化修饰的研究内容与方法,并综述了最近的研究进展。

关 键 词:糖基化  糖蛋白  糖链  质谱  糖基化工程
收稿时间:2005-10-24
修稿时间:2005-10-24

Detection of Protein Glycosylation Modifications and Its Applications
Zhang Qian,Yang Zhen,Zhang Yanzhen,Wang Aili,An Xueli,Yan Yueming. Detection of Protein Glycosylation Modifications and Its Applications[J]. Biotechnology Bulletin, 2006, 0(1): 46-49
Authors:Zhang Qian  Yang Zhen  Zhang Yanzhen  Wang Aili  An Xueli  Yan Yueming
Affiliation:College of Life Science, Capital Normal University, Beijing 100037
Abstract:Glycosylation is one of the most important post-translational modifications of the protein,which is related to many activities of life.With the development of the proteomics,the studies of the glycosylation are attached more and more importance.This article has introduced the approaches for determination of the specific-glycosylation-site,the assay of sugar chains of the glycoprotein,the glycosylation engineering,and reviewed the progresses in their applications.
Keywords:Glycosylation Glycoprotein Sugar chain MS Glycosylation engineering
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