|
|||||
|
|
2-(2-Hydroxy-3-alkoxyphenyl)-1H-benzimidazole-5-carboxamidine derivatives as potent and selective urokinase-type plasminogen activator inhibitors |
|
| Authors: | Mackman Richard L Hui Hon C Breitenbucher J Guy Katz Bradley A Luong Christine Martelli Arnold McGee Danny Radika Kesavan Sendzik Martin Spencer Jeffrey R Sprengeler Paul A Tario James Verner Erik Wang Jing |
| Institution: | Celera, 180 Kimball Way, South San Francisco, CA 94080, USA. |
| Abstract: | The development of potent and selective urokinase-type plasminogen activator (uPA) inhibitors based on the lead molecule 2-(2-hydroxy-3-ethoxyphenyl)-1H-benzimidazole-5-carboxamidine (3a) is described. |
| Keywords: | |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |