An assessment of the models of thin filament of the sarcomere using small-angle X-ray data on rabbit relaxed muscle |
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| Authors: | N A Koubassova |
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| Institution: | (1) Institute of Mechanics, Moscow State University, Michurinskii pr. 1, Moscow, 119992, Russia |
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| Abstract: | Models of a thin filament based on various G-actin atomic structures and modes of their packing into helical structures were considered. The calculated intensities of actin layer lines were compared with the X-ray data for thin fiber bundles of a relaxed rabbit skeletal muscle. The effect of the main components of thin filament on the intensity of actin layer lines was also analyzed. The F-actin PDB 3BYH model gave the best fit to the experimental data. |
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| Keywords: | muscle X-ray diffraction actin troponin tropomyosin mathematical modeling |
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