CLEAN: CLustering Enrichment ANalysis |
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Authors: | Johannes M Freudenberg Vineet K Joshi Zhen Hu Mario Medvedovic |
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Institution: | (1) Laboratory for Statistical Genomics and Systems Biology, Department of Environmental Health, University of Cincinnati College of Medicine, 3223 Eden Av. ML 56, Cincinnati, OH 45267-0056, USA |
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Abstract: | Background Integration of biological knowledge encoded in various lists of functionally related genes has become one of the most important
aspects of analyzing genome-wide functional genomics data. In the context of cluster analysis, functional coherence of clusters
established through such analyses have been used to identify biologically meaningful clusters, compare clustering algorithms
and identify biological pathways associated with the biological process under investigation. |
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Keywords: | |
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