| 人体肠道宏基因组生物信息分析方法 |
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| 引用本文： | 郑智俊,黄云,秦楠. 人体肠道宏基因组生物信息分析方法[J]. 微生物学报, 2018, 58(11): 2020-2032 |
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| 作者姓名： | 郑智俊 黄云 秦楠 |
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| 作者单位： | 上海锐翌生物科技有限公司, 上海 201114,上海锐翌生物科技有限公司, 上海 201114,上海锐翌生物科技有限公司, 上海 201114;同济大学附属第十人民医院, 上海 200072 |
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| 基金项目： | 国家自然科学基金（31670118） |
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| 摘 要： | 最近5年来,微生物组与人体健康之间的微妙关系已成为全球研究热点,特别是基于高通量测序的宏基因组技术推动了这个领域的发展。然而宏基因组生物信息学分析往往是开展研究过程中的难点。本文对宏基因组生物信息常规分析方法进行了介绍。
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| 关 键 词： | 宏基因组 生物信息分析 微生物组 高通量 |
| 收稿时间： | 2018-03-15 |
| 修稿时间： | 2018-07-24 |
A review of bioinformatic methodologies in metagenomics |
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| Zhijun Zheng,Yun Huang and Nan Qin. A review of bioinformatic methodologies in metagenomics[J]. Acta microbiologica Sinica, 2018, 58(11): 2020-2032 |
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| Authors: | Zhijun Zheng Yun Huang Nan Qin |
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| Affiliation: | Realbio Genomics Institute, Shanghai 201114, China,Realbio Genomics Institute, Shanghai 201114, China and Realbio Genomics Institute, Shanghai 201114, China;Shanghai Tenth People''s Hospital Affiliated to Tongji University, Shanghai 200072, China |
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| Abstract: | In the last five years, the delicate relationship between microbiota and human health has become a global research focus. In particular, development of metagenomics that is based on next-generation high-throughput sequencing technology has greatly advanced the field. However, bioinformatic analyses are often a great challenge for metagenomic studies. Here we review the common analytic methods for metagenomics. |
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| Keywords: | metagenomics bioinformatics microbiota high-throughput sequencing |
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