Inclusion complexes of N-sulfamoyloxazolidinones with beta-cyclodextrin |
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Authors: | Kadri Mekki Djemil Rayenne Abdaoui Mohamed Winum Jean-Yves Coutrot Frédéric Montero Jean-Louis |
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Affiliation: | Laboratoire de Chimie Appliquée, Université de Guelma, BP401, Guelma 24000, Algeria. mekadri@yahoo.fr |
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Abstract: | A study of inclusion complexes of six N-sulfamoyloxazolidinone derivatives with beta-cyclodextrin is described. The inclusion complexes were prepared in solution and in solid state with stoichiometry host-guest 1:1, and characterized. In solution, the complexation was carried out by spectrophotometric measurements at 25 degrees C. The stoichiometries and stability constants of complexes at various pHs have been determined using second-derivative spectrophotometry UV-vis. Hydrophobic properties of N-sulfamoyloxazolidinones are improved following their inclusion into beta-CD. |
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