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Herpes Simplex Virus 1 VP22 Inhibits AIM2-Dependent Inflammasome Activation to Enable Efficient Viral Replication
Authors:Yuhei Maruzuru  Takeshi Ichinohe  Ryota Sato  Kensuke Miyake  Tokuju Okano  Toshihiko Suzuki  Takumi Koshiba  Naoto Koyanagi  Shumpei Tsuda  Mizuki Watanabe  Jun Arii  Akihisa Kato  Yasushi Kawaguchi
Affiliation:1. Division of Molecular Virology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo 108-8639, Japan;2. Department of Infectious Disease Control, International Research Center for Infectious Diseases, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo 108-8639, Japan;3. Japan Society for the Promotion of Science, Chiyoda-ku, Tokyo 102-0083, Japan;4. Division of Innate Immunity, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo 108-8639, Japan;5. Department of Bacterial Pathogenesis, Infection and Host Response, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo 113-8549, Japan;6. Department of Biology, Faculty of Science, Kyushu University, Nishi-ku, Fukuoka 819-0395, Japan
Abstract:
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  • Keywords:HSV-1  herpes simplex virus  inflammasome  immune evasion  AIM2
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