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Leukotriene B4-Mediated Neutrophil Recruitment Causes Pulmonary Capillaritis during Lethal Fungal Sepsis
Authors:Esther KS Lee  Mark R Gillrie  Lu Li  Jason W Arnason  Jung Hwan Kim  Liane Babes  Yuefei Lou  Amir Sanati-Nezhad  Stephen K Kyei  Margaret M Kelly  Christopher H Mody  May Ho  Bryan G Yipp
Institution:1. Calvin, Phoebe and Joan Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada;2. Department of Critical Care Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada;3. Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada;4. Department of Medicine, Division of Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada;5. Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada;6. Department of Mechanical and Manufacturing Engineering, BioMEMS and Bioinspired Microfluidic Laboratory, Center for BioEngineering Research and Education, University of Calgary, Calgary, AB, Canada;7. Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada
Abstract:
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  • Keywords:sepsis  neutrophils  pulmonary inflammation  swarming  capillaritis  leukotriene  innate immunity  host defense  fungal infection
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