Babesia bovis host cell recognition proteins. |
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Authors: | G R Bushell B Garrone B V Goodger I G Wright B P Dalrymple |
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Affiliation: | Division of Science and Technology, Griffith University, Nathan, Queensland, Australia. |
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Abstract: | Babesia bovis enters host erythrocytes by invagination but nothing is known of the proteins involved. By means of metabolic labelling, differential centrifugation in oil and salt elution, a number of babesial proteins have been shown to bind to bovine erythrocytes. Strong binding is evidenced only by a 38/19 kDa pair. Preliminary experiments indicate that these two proteins also bind to human erythrocytes, although apparently to a lesser extent. |
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