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Direct observation and unambiguous inference
Authors:Michael?Knapp,Warren?Ewens  author-information"  >  author-information__contact u-icon-before"  >  mailto:wewens@sas.upenn.edu"   title="  wewens@sas.upenn.edu"   itemprop="  email"   data-track="  click"   data-track-action="  Email author"   data-track-label="  "  >Email author
Affiliation:(1) Institute for Medical Biometry, Informatics University of Bonn, D-53105 Bonn, Germany;(2) Department of Biology, University of Pennsylvania, PA 19104, Philadelphia, USA
Abstract:In science, it sometimes occurs that an event is directly observed, and on other occasions that it is not directly observed but one can make the unambiguous inference that it has occurred. Is there any difference concerning the analysis of data arising from these two situations? In this note we show that there is such a difference in one case arising frequently in genetics. The difference derives from the fact that the ability to make the unambiguous inference arises only from a restricted form of data.
Keywords:inference  observation  transmission/disequilibrium  disease locus  gene transmission
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