Immunochemical characterization of aldo-keto reductases from human tissues |
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| Authors: | H P Wirth B Wermuth |
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| Affiliation: | Medizinisch-chemisches Institut der Universität, Bühlstrasse 28, CH-3012 Bern, Switzerland |
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| Abstract: | Aldose reductase, aldehyde reductase and carbonyl reductase constitute a family of monomeric NADPH-dependent oxidoreductases with similar physical and chemical properties. Characterization of the enzymes from human tissues by immunotitration and an enzyme immunoassay indicated that, despite their apparent likeness, the three reductases do not cross-react immunochemically. |
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