Amino acids and peptides: Part XLIII. Structure-activity studies in the bradykinin series: Synthesis of analogs modified in position |
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| Authors: | Virander S Chauhan Geoffrey T Young |
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| Institution: | The Dyson Perrins Laboratory, Oxford University, Oxford, U.K. |
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| Abstract: | β-Alanyl-, acetimidoyl-, and carbamoyl-bradykinin (IV), (V), and (VI), respectively] have been synthesized by the picolyl ester method. The first two analogs have very low smooth muscle contracting activity, but the carbamoyl derivative is as fully active as bradykinin itself. |
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| Keywords: | To whom correspondence should be addressed |
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