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Synthesis of selenium-containing amino acid analogues and their biological study |
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| Authors: | |
| Institution: | 1.Chemistry Department, Faculty of Science,Taif University,Taif,Kingdom of Saudi Arabia;2.Chemistry Department, Faculty of Applied Science,Assiut University,Assiut,Egypt;3.Chemistry Department, Faculty of Applied Science,Zagazig University,Zagazig,Egypt;4.Chemistry Department, Faculty of Applied Science,Port Said University,Port Said,Egypt |
| Abstract: | Synthesis of selenium-containing amino acid analogues is described. These compounds were prepared in a concise and short synthetic route in good yields by nucleophilic substitution reaction of pyridineselenol and quinolineselenol derivatives with N-phthaloylglycyl chloride followed by hydrazinolysis. The newly synthesized compounds were screened against different strains of bacteria and fungi. |
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