| MALDI-TOF MS技术在临床病原真菌鉴定中的应用进展 |
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| 引用本文： | 王冲,占萍,刘维达. MALDI-TOF MS技术在临床病原真菌鉴定中的应用进展[J]. 中国真菌学杂志, 2013, 0(6): 369-373 |
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| 作者姓名： | 王冲 占萍 刘维达 |
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| 作者单位： | 中国医学科学院北京协和医学院皮肤病研究所,南京210042 |
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| 基金项目： | 卫生部临床学科重点项目（2010-2012）,科技部重大专项子课题（2012ZX09301002005001005） |
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| 摘 要： | 基质辅助激光解吸电离飞行时间质谱技术（MALDI-TOF-MS）目前是一种快速而可靠的微生物鉴定方法.随着可鉴定真菌谱的完善,MALDI-TOF MS技术已逐步应用于临床常见致病酵母菌、酵母样真菌和丝状菌的鉴定中,本文将就此做一综述.
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| 关 键 词： | 基质辅助激光解吸电离飞行时间质谱 真菌 鉴定 |
Advances in the application of Matrix-assisted laser desorption ionization time-of-flight mass spectrometry for identification of clinically pathogenic fungi |
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| WANG Chong;ZHAN Ping;LIU Wei-da. Advances in the application of Matrix-assisted laser desorption ionization time-of-flight mass spectrometry for identification of clinically pathogenic fungi[J]. Chinese JOurnal of Mycology, 2013, 0(6): 369-373 |
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| Authors: | WANG Chong ZHAN Ping LIU Wei-da |
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| Affiliation: | WANG Chong;ZHAN Ping;LIU Wei-da(Department of mycology,Institute of Dermatology,Chinese Academy of Medical Sciences ＆ Peking Union Medical College, Nanjing 210042, China) |
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| Abstract: | Matrix-assisted laser desorption ionization-time of flight mass spectrometry （MALDI-TOF MS）-based systems is a rapid and reliable method in identification of microorganism.With the improvement of identifiable fungal species spectrum,the application of MALDI-TOF MS systems have been introduced to identification of clinically pathogenic yeasts,yeast-like fungi,filamentous fungi and dermatophytes. |
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| Keywords: | Matrix-assisted laser desorption ionization-time of flight mass spectrometry （MALDI-TOF MS） identification |
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