Social behavior of the yeast protein-protein interaction network |
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Authors: | Seshasayee Aswin Sai Narain |
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Institution: | EMBL-EBI, Wellcome Trust Genome Campus, Hinxton, Cambridge CB101SD, UK. aswin@ebi.ac.uk |
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Abstract: | Protein-protein interaction networks are useful in contextual annotation of protein function and in general to achieve a system-level understanding of cellular behavior. This work reports on the social behavior of the yeast protein-protein interaction network and concludes that it is non-random. This work, while providing an analysis of organization of genes into functional societies, can potentially be useful in assessing the accuracy of contextual gene annotation based on such interaction networks. |
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