Thermal analysis of the human intervertebral disc

Intervertebral disc (IVD) degeneration is one of the most common musculuskeletal disorders affecting western society. Degeneration alters the morphology and the mechanical properties of the discs. According to previous reports, DSC proved to be a suitable method for the demonstration of thermal consequences of local as well as global conformational changes in the structure of the human intervertebral discs. In the present study, a wide spectrum of degenerated IVD was examined by DSC. The results suggest that definitive differences exist between the stages of disc degeneration in calorimetric measures.