A gene involved in the metabolic control of ppGpp synthesis |
| |
Authors: | Chia Chu Pao and Jonathan Gallant |
| |
Affiliation: | (1) Department of Genetics, University of Washington, 98195 Seattle, Washington, USA |
| |
Abstract: | Summary A genetic locus has been identified which controls the basal synthesis of ppGpp in growing E. coli. Cells carrying a recessive allele of the relX gene have a very low concentration of ppGpp during balanced growth, and fail to accumulate ppGpp in response to carbon/energy source downshift. Moreover, the recessive relX allele renders the cells unable to grow at 42° C and, when coupled with relA, makes the cells sensitive to the presence of leucine in minimal medium. RelX is cotransduced with fuc and relA and located at approximately 59.4 min on the E. coli genetic map. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|