| NKT细胞在动脉粥样硬化中的作用 |
| |
| 引用本文： | 王伟,杜美,陈正望. NKT细胞在动脉粥样硬化中的作用[J]. 生物磁学, 2011, 0(1): 158-160 |
| |
| 作者姓名： | 王伟 杜美 陈正望 |
| |
| 作者单位： | 华中科技大学生命科学与技术学院生物物理所,湖北武汉430074 |
| |
| 基金项目： | 国家自然科学基金（30370647 3470823） |
| |
| 摘 要： | 然杀伤T细胞（natural killer T cell,NKT细胞）是一种特殊的淋巴细胞亚群,具有部分T细胞和NK细胞的特征。与这些细胞不同的是,NKT细胞不仅能够识别醣脂类抗原,还在激活后产生促炎症因子和抗炎症因子。由于这些特性,NKT细胞在炎症和免疫方面的研究越来越热。动脉粥样硬化是一种受免疫调节的炎性疾病,因此对NKT细胞在该疾病中作用的研究也逐渐开展起来。
|
| 关 键 词： | 自然杀伤T细胞 免疫反应 双向调节 动脉粥样硬化 |
Roles of NKT cells in atherosclerosis |
| |
| WANG Wei,DU Mei,CHEN Zheng-wang. Roles of NKT cells in atherosclerosis[J]. Biomagnetism, 2011, 0(1): 158-160 |
| |
| Authors: | WANG Wei DU Mei CHEN Zheng-wang |
| |
| Affiliation: | △(College of Life Science and Technology,Institute of Biophysics and Biochemistry,Huazhong University of Science and Technology,Wuhan,430074,China) |
| |
| Abstract: | Natural killer T cell（NKT cell） is a specialized subset of lymphocytes,which shares with some characteristics of both T cell and Natural kill cell（NK cell）.Nevertheless,unlike both of them,NKT cell can recognize glycolipid antigens,and produce some pro-inflammatory and anti-inflammatory cytokines on activation.Due to these characteristics,more and more researches about NKT cells in inflammatory and immune aspects are turned up.It is becoming very clear that atherosclerosis is a chronic inflammatory disease with both innate and adaptive immunity in pathological mechanism.Therefore,researches on roles of NKT cell in the disease are getting hot. |
| |
| Keywords: | NKT cell Immune response Two-way adjustment Atherosclerosis |
| 本文献已被 维普 等数据库收录！ |
|
