运动对细胞凋亡的影响 |
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引用本文: | 李军勇,伊力哈木·托合提.运动对细胞凋亡的影响[J].生物磁学,2011(3):593-597. |
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作者姓名: | 李军勇 伊力哈木·托合提 |
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作者单位: | 新疆医科大学第二附属医院骨科,新疆乌鲁木齐830000 |
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基金项目: | 新疆维吾尔自治区高校科研计划科学研究重点项目(XJEDU2008S37) |
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摘 要: | 细胞凋亡是一种由基因控制的细胞自主性死亡过程,其性质为生理性细胞死亡。细胞凋亡的研究已成为生物医学领域中最热门的课题之一。运动可以诱导细胞凋亡,细胞凋亡发生的比率和程度与运动形式、运动强度和运动持续时间有关,其机制可能主要包括以下方面:影响凋亡相关基因、自由基的介导使氧化与抗氧化系统失衡,损伤线粒体的结构和功能以及机械损伤。为此就运动对细胞凋亡影响的一些新的研究进展进行了综述。
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关 键 词: | 细胞凋亡 运动 骨骼肌 免疫系统 心肌 肝细胞 |
Effects of Exercise on Apoptosis |
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Institution: | LI Jun-yong,YIlIHAMU·Tuoheti(Department of osteology,Second Hospital of Xinjiang Medical University,Xinjiang Urumqi,830000,China) |
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Abstract: | Apoptosis is an initiative cell death process that is controlled by gene and it is a kind of physiological cell death.Apoptosis has become one of study warm points and forward positions in biology and medicine.Apoptosis of cell was induced by exer-cise and the incidence and level of apoptosis related to the mode,intensity and sustained time of exercise.The main possible mechanisms consisted of the followings:factors of apoptosis-related gene,free radical inducing resulted un-equilibrium between oxidant and antioxi-dant system,mitochondrial structure and function injury,as well as mechanical injury.This paper reviewed some new progress about effects of exercise on apoptosis. |
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Keywords: | apoptosis exercise muscle immune system myocardium hepatocyte |
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