Demonstration of postural asymmetry factors in a hypophyseal tissue culture as affected by the cerebrospinal fluid of cats with unilateral damage to the hemispheric cortex

It has been experimentally established that special hypophysiotropic factors--precursors of pose asymmetry factors (PAF) are found in the cerebrospinal fluid of donor animals with cortical lesions during the first postoperative hours. These factors, being specific for the location of the cortical lesion in donor animals, appear to be hypophysiotropic peptide substances inducing the production of corresponding PAF by hypophysial cells. The production of certain PAF by the rat hypophysial tissue cultures under the influence of cerebrospinal fluid from cats gives evidence in favour of species nonspecificity of PAF inductors.