The DNA of CAENORHABDITIS ELEGANS |
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| Authors: | J E Sulston and S Brenner |
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| Institution: | Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, England |
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| Abstract: | Chemical analysis and a study of renaturation kinetics show that the nematode, Caenorhabditis elegans, has a haploid DNA content of 8 x 10(7) base pairs (20 times the genome of E. coli). Eighty-three percent of the DNA sequences are unique. The mean base composition is 36% GC; a small component, containing the rRNA cistrons, has a base composition of 51% GC. The haploid genome contains about 300 genes for 4S RNA, 110 for 5S RNA, and 55 for (18 + 28)S RNA. |
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