Expression and characterization of novel ovine orthologs of bovine placental prolactin-related proteins |
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| Authors: | Koichi Ushizawa Toru Takahashi Misa Hosoe Katsuhiro Ohkoshi Kazuyoshi Hashizume |
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| Institution: | (1) Reproductive Biology Research Unit, Division of Animal Sciences, National Institute of Agrobiological Sciences, 2 Ikenodai, Tsukuba, Ibaraki 305-8602, Japan;(2) Department of Veterinary Medicine, Faculty of Agriculture, Iwate University, 3-18-8 Ueda, Morioka, Iwate 020-8550, Japan |
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| Abstract: | Background The prolactin-related proteins (PRPs) are non-classical placental-specific members of the prolactin/growth hormone family.
Among ruminants, they are expressed in the cotyledonary villi of cattle and goat. We investigated placental PRP in sheep in
order to gain a comprehensive understanding of the function and evolution of these molecules. We also examined the sequence
properties, expression and lactogenic activation of the cloned genes. |
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