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Wound healing potential of chitosan and N-sulfosuccinoyl chitosan derivatives |
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| Authors: | T P Alekseeva A A Rakhmetova O A Bogoslovskaya I P Olkhovskaya A N Levov A V Il’ina V P Varlamov T A Baitukalov N N Glushchenko |
| Institution: | 1.Institute of Energy Problems of Chemical Physics,Russian Academy of Science,Moscow,Russia;2.Peoples’ Friendship University of Russia,Moscow,Russia;3.Center Bioinzeneria,Russian Academy of Science,Moscow,Russia;4.Familiprix Lasalle,Lasalle, Montreal-Ouest,Canada |
| Abstract: | Comparative study of chitosan wound healing properties and its synthesized derivatives in MC-100 gel was carried out using the model of experimental full thickness skin wounds. It was determined that N-sulfosuccinoyl chitosan derivatives added into the gel in a concentration of 0.05% possess the higher wound healing activity in comparison with other chitosan derivatives and decrease the half-healing period of wounds 2–3 times in comparison with the control. |
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