Recombination between two mouse t haplotypes (t w12 tf) and t Lub-1) : Mapping. of the H-2 complex relative to centromere and tufted (tf) locus |
| |
Authors: | Marika Plat Hubert Condamine |
| |
Affiliation: | (1) Hôpital Saint Louis, U93 INSERM, 2, Place du Dr. A. Fournier, 75475 Paris Cedex 10, France;(2) Service de Génétique cellulaire du Collège de France et de l'Institut Pasteur, 25, rue du Dr. Roux, 75724 Paris Cedex 15, France |
| |
Abstract: | A monoclonal antibody known to recognize the H-2.m3 specificity is shown to react with the class I H-2 product of tLub-1 but not tw12tf mice. This reagent was used to study the segregation of the H-2 complex in the progeny of tLub-1 +/tww12tf females. The most straightforward interpretation of the results presented here is that these t haplotypes carry an H-2 complex located between the centromere and tufted locus. Possible consequences of such a location with regard to the recombination between t haplotypes and chromosome 17 from laboratory mice are discussed. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|