News & Notes: Stochastic Nucleosome Positioning in a Yeast Chromatin Region Is Not Dependent on Histone H1 |
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| Authors: | Sergi Puig Emilia Matallana José E Pérez-Ortín |
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| Institution: | (1) Departamento de Bioquímica y Biología Molecular, Universitat de València, and Instituto de Agroquímica y Tecnología de Alimentos, C.S.I.C., Valencia, Spain , ES |
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| Abstract: | To gain a better understanding of the function of the yeast histone H1, its role in nucleosome positioning was studied. With
this objective in mind, we analyzed a chromatin region of the yeast Chromosome (Chr) IX, in which there are two closely packed
open reading frames (ORFs), POT1 and YIL161w. This locus shows a regular ladder of 13 stochastically positioned nucleosomes, which is unaffected by the absence of the
HHO1 gene. This suggests that histone H1 has no effect on nucleosome positioning in yeast.
Received: 30 December 1998 / Accepted: 6 May 1999 |
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