| 荷瘤SCID-hu鼠模型及其肿瘤实验研究现状 |
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| 引用本文： | 周海滨,颜汝平,王剑松.荷瘤SCID-hu鼠模型及其肿瘤实验研究现状[J].中国实验动物学杂志,2009(10):64-67. |
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| 作者姓名： | 周海滨 颜汝平 王剑松 |
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| 作者单位： | 昆明医学院第二附属医院泌尿外科,云南省泌尿外科研究所,昆明650101 |
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| 摘 要： | 严重联合免疫缺陷鼠（severe combined immune deficiency mice,SCID）具有T、B淋巴细胞联合免疫缺陷等生物学特性,可以将人类有关免疫细胞、免疫组织和器官移植入其体内进行人免疫功能重建-SCID-hu鼠。荷瘤SCID-hu鼠模型为人类肿瘤的发病机制、生物治疗等方面的研究提供了良好的实验平台。
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| 关 键 词： | 严重联合免疫缺陷鼠 小鼠 SCID-hu 模型 动物 |
Current Situation of Research on Humanized SCID Mice Bearing Tumor Model and Its Tumor Experiment |
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| ZHOU Hai-bin,YAN Ru-ping,WANG Jian-song.Current Situation of Research on Humanized SCID Mice Bearing Tumor Model and Its Tumor Experiment[J].Chinese Journal of Laboratory Animal Science,2009(10):64-67. |
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| Authors: | ZHOU Hai-bin YAN Ru-ping WANG Jian-song |
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| Institution: | ( Department of Urology, the Second Affiliated Hospital of Kunming Medical College Urology Research Institute of Yunnan Province, Kunming 650101, China) |
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| Abstract: | Severe combined immunodeficient mice（SCID） have biological characteristics of T,B lymphocytes combined immune deficiency.Human immune cells,tissues and organs are transplanted into their bodies to reconstruct human immune function-SCID-hu mice.In recent years,many tumor-bearing SCID-hu mouse models were established,which provided a good experimental platform for the research of pathogenesis of human tumors and biological treatments. |
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| Keywords: | Severe combined immunodeficient mice（SCID） Mice SCID-hu Model animal |
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