| 实验性链脲佐菌素诱导的大、小鼠糖尿病动物模型研究进展 |
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| 引用本文： | 金勇,朱勇,吴南翔.实验性链脲佐菌素诱导的大、小鼠糖尿病动物模型研究进展[J].中国实验动物学杂志,2009(3):80-82. |
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| 作者姓名： | 金勇 朱勇 吴南翔 |
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| 作者单位： | 浙江省医学科学院卫生学研究所,杭州310013 |
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| 基金项目： | 浙江省科技厅项目（2005F13029）;浙江省医药卫生科学研究基金（2005A003）. |
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| 摘 要： | 糖尿病正呈快速上升趋势，而糖尿病的病因、发病机制尚未完全阐明，糖尿病及其并发症的预防和治疗仍不完善。因此，在糖尿病研究领域优化糖尿病实验动物模型的研究，寻找更接近人类糖尿病自然发病过程的动物模型，对于深入研究糖尿病具有重要的科学意义。
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| 关 键 词： | 实验性糖尿病 大鼠 小鼠 链脲佐菌素 |
Advances in Experimental Streptozotocin-induced Rodent Models of Diabetes Mellitus |
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| JIN Yong,ZHU Yong,WU Nan-xiang.Advances in Experimental Streptozotocin-induced Rodent Models of Diabetes Mellitus[J].Chinese Journal of Laboratory Animal Science,2009(3):80-82. |
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| Authors: | JIN Yong ZHU Yong WU Nan-xiang |
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| Institution: | ( Institute of Hygiene, Zhejiang Academy of Medical Sciences, Hangzhnu 310013, China) |
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| Abstract: | The prevalence of both type 1 and type 2 diabetes mellitus have been increasing beyond our prediction. While the etiology and pathogenesis of diabetes mellitus, especially type 2 diabetes, have not been completely clarified, the prevention and treatments of diabetes and its complications have a long way to go for perfect goals. Therefore, improving experimental diabetic animal models and looking for excellent models of human-like pathogenic process of diabetes become much more significant. |
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| Keywords: | Experimental diabetes Rat Mouse Streptozotocin |
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